PB2262 HEALTHCARE RESOURCE UTILIZATION (HRU) ASSOCIATED WITH MINIMAL RESIDUAL DISEASE (MRD) STATUS IN ADULTS WITH B-CELL PRECURSOR (BCP) ACUTE LYMPHOBLASTIC LEUKEMIA (ALL)

Evaluation of Relationship between Minimal Residual Disease (MRD) and Relapse in Childhood Acute Lymphoblastic Leukemia (ALL) Using Quantitative Fluorescent PCR

Whole-genome DNA methylation characteristics in pediatric precursor B cell acute lymphoblastic leukemia (BCP ALL)

In addition to genetic alterations, epigenetic abnormalities have been shown to underlie the pathogenesis of acute lymphoblastic leukemia (ALL)-the most common pediatric cancer. The purpose of this study was to characterize the whole genome DNA methylation profile in children with precursor B-cell ALL (BCP ALL) and to compare this profile with methylation observed in normal bone marrow samples....

Study of Minimal Residual Disease in Adults with B-Lineage Acute Lymphoblastic Leukemia by Flowcytometry

Background: After achieving morphological remission, existence of few number of leukemic cells in the patient’s blood represents the minimal residual disease (MRD) and its monitoring helps in evaluating early treatment response and future relapse. Patients and methods: Eighty seven newly diagnosed (B-ALL) cases were enrolled in the present study in the time period from October 2013 to October 2...

evaluation of relationship between minimal residual disease (mrd) and relapse in childhood acute lymphoblastic leukemia (all) using quantitative fluorescent pcr

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flowcytometric and dna analysis minimal residual disease (mrd) in childhood b-lineage lymphoblastic leukemia

background: induction chemotherapy for acute lymphoblastic leukemia achieves complete remis sion in over 90% of children. it is apparent therefore that many patients in clinical remission and with out residual disease detectable by conventional light microscopy of peripheral blood or bone marrow films still harbor viable cells of the original disease mrd analysis does have a useful role to play...